Blurry Vision Making Daily Life Harder?

If corneal swelling is keeping you from reading, driving, or doing the things you love — a clinical research study may be able to help. … See if you qualify in under 2 minutes

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WHO CAN PARTICIPATE?

Here are the qualifications potential participants must meet in order to join a clinical research study for corneal edema:

Have corneal swelling due to corneal endothelial dysfunction, including Fuchs’ Dystrophy
Can lie face-down for 3 hours after surgery
Have eye measurements (vision and corneal thickness) within the study’s required range
Have had cataract surgery

Additional criteria apply. A study doctor will determine final eligibility based on full medical and eye-health criteria.

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How Clinical
Trials Work

Thank you for your interest in learning more about clinical trials for corneal edema! Every day, academic institutions, pharmacological organizations and private research facilities across the country are diligently working on making scientific breakthroughs in various clinical trials.

Here’s a look at what a clinical trial for corneal edema might involve:

A principal investigator, or PI, is the physician in charge at a designated study site for the clinical trial who is responsible for coordinating and overseeing the clinical study. That individual carries out what is called a protocol.

Protocol is a document that describes how the trial is designed, and outlines how it should be carried out.

Clinical trials, also called research studies or clinical studies, can be either interventional or non-interventional. Interventional studies means that they test out an intervention, like a drug, procedure or medical device. Non-interventional studies, also called observational studies, don’t test potential treatments. Instead, researchers observe the participants over a period of time, and track health outcomes.

Clinical Trials Make A Difference

Participation in a clinical study provides valuable information that could eventually lead to a better treatment and — with the right advancements — to better outcomes. Take our short survey to see if you or a loved one may be a good fit. There is no obligation to enroll.

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Understanding Corneal Edema

WHAT IS IT?

Corneal edema is swelling of the clear front part of the eye, often causing blurry vision, discomfort, and light sensitivity. It can make daily activities like reading or driving difficult. When caused by endothelial dysfunction, the inner layer of the cornea does not work properly, leading to fluid buildup and vision problems.

HOW IS IT TREATED?

Corneal swelling may be treated with a range of therapies, including saline drops, corticosteroids, or ultimately corneal transplant surgery.¹ In recent years, many people have also turned to clinical trials to better understand this condition, and how best to help navigate it.

HOPE FOR THE FUTURE

Clinical trials play a vital role in evaluating the safety and effectiveness of these potential treatments and in helping to bring them to patients who need them. Patients living with corneal edema due to corneal endothelial dysfunction could potentially play a part in that research effort, and contribute to advancing treatment options that may one day be able to help.

44,000+

Number of people with eye conditions who need corneal transplants each year in the United States.²

FREQUENTLY ASKED QUESTIONS

What are the symptoms of corneal edema?

Signs may include:¹

Blurred vision.
Sensitivity to light (photophobia).
Seeing halos around lights.
Eye pain or discomfort, feeling like something is in your eye.

Source: https://my.clevelandclinic.org/health/diseases/25203-corneal-edema

Who may be a good candidate to apply for this study?

This trial is enrolling people aged 18 and older who:

Have corneal swelling due to corneal endothelial dysfunction, including Fuchs’ Dystrophy
Can lie face-down for 3 hours after surgery
Have eye measurements (vision and corneal thickness) within the study’s required range
Have had cataract surgery

Additional criteria apply. A study doctor will determine final eligibility based on full medical and eye-health criteria.

What will happen during a clinical study for corneal edema?

Most clinical trials will involve screening to confirm that a potential patient is, in fact, a match for that study’s criteria. Once verified and the patient has signed an Informed Consent Form, which clearly provides the details and purpose of the study to that individual and what it involves, participants can expect to attend scheduled appointments at a study clinician’s site. They may also receive a study treatment (also called an investigational product) or potentially a control (also known as placebo which contains no active treatment) and undergo additional screening and follow-up monitoring. Throughout the study, participants should experience a professional clinical environment, and be treated with compassion and respect.

Are there any costs to participate in this study?

There is no cost to participate in a clinical trial. Participants receive all study-related medical care and medications for the duration of the study at no cost. Likewise in many instances, participants may also receive reimbursement for time and travel.

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